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Lysergic acid

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D-Lysergic acid
Chemical name 6-Methyl-9,10-didehydro-
ergoline-8-carboxylic acid
or
7-methyl-4,6,6a,7,8,9-
hexahydro-indolo[4,3-fg]
quinoline-9-carboxylic acid
Chemical formula C16H16N2O2
Molecular mass 268.31 g/mol
Melting point 238 - 240 C
CAS number 82-58-6, 478-95-5,
6915-32-8, 23953-76-6,
68985-97-7, 68985-98-8
SMILES O=[C@](O)[C@H]1CN(C)
[C@](C2=C1)([H])CC3=C
NC4=C3C2=CC=C4
Missing image
D-lysergic_acid.png
Chemical structure of d-lysergic acid


Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and some plants. Amides of lysergic acid, commonly called lysergamides, are widely used as pharmaceuticals and as hallucinogenic drugs (LSD). Lysergic acid is usually produced by hydrolysis of lysergamides, but can also be synthesized in the laboratory by a complex total synthesis. Lysergic acid is a chiral compound with two stereocenters. The isomer with inverted configuration at carbon atom 8 close to the carboxy group is called isolysergic acid. Inversion at carbon 5 close to the nitrogen atom leads to L-lysergic acid and L-isolysergic acid, respectively. Lysergic acid is listed as a Table I precursor under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances [1] (http://www.incb.org/pdf/e/list/red.pdf).


See also

Template:Hallucinogenic lysergamidesTemplate:Hallucinogen-stub

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